Support this blog by donation
If you found the contents of this blog useful, you can support it with a small donation which will be used to cover management costs and encourage future developments. Se hai trovato utili i contenuti di questo blog, puoi supportarlo con una piccola donazione che verrà utilizzata per coprire i costi di gestione e incentivare progetti futuri. Wenn Sie den Inhalt dieses Blogs nützlich fanden, können Sie ihn mit einer kleinen Spende unterstützen, die zur Deckung der Verwaltungskosten und zur Förderung zukünftiger Projekte verwendet wird.
- Follow Danilo Roccatano on WordPress.com
Top Posts & Pages
- The calculation of the Madelung constant
- Il calcolo della entalpia reticolare: il ciclo di Born-Haber
- Berechnung der Konstante von Madelung
- Physical Chemistry: The Simple Hückel Method
- Modeling Natural Pattens and Forms I: Sunflowers Florets and the Golden Ratio
- The Lissajous-Bowditch Curves
- The Calculation of the Lattice Energy: The Born-Haber Cycle
- The First 150 Years of the Periodic Table of the Elements
- Modelling Natural Shapes: (Easter) Eggs 2020
Daily Archives: May 6, 2017
Lignin Peroxidase (LiP), a hemoprotein isolated from the ligninolytic cultures of the white-rot fungus Phenerochaete Chrysosporium is one of the most important lignin-degrading enzymes. We have investigated the dynamical and structural properties of lignin peroxidase and its Trp171Ala mutant in aqueous … Continue reading
Human neutrophil collagenase (HNC, MMP8) is one of the target enzymes for drug treatment of pathologic extracellular matrix degradation. Peptidomimetic inhibitors bind in the S-side of the enzyme active site occupying the S1 primary specificity pocket by their large hydrophobic … Continue reading
Myoglobin is a small ancient protein of ~150 amino acids specialized in the transport of respiratory gases to muscular tissues and back to the lungs of the superior organisms. Even though, it was one of the first protein having the three-dimensional … Continue reading
The nucleosome core particle (NCP) constitutes the basic structural unit of the eukaryotic chromatin. It consists of 147 base-pairs (bp) of DNA wrapped in a left-handed superhelix 1.65 times around a histone octamer. The octamer is formed by two copies … Continue reading
β-lactamases are enzymes produced by bacteria (also known as penicillinase) that provide multi-resistance to β-lactam antibiotics such as penicillins, cephamycins, and carbapenems.
The citrate synthase is a model enzyme for the study of the dynamics of domain motions. It is a key protein in the metabolic cycle of the cell (Krebs cycle) as it catalyzes the Claisen condensation of acetyl-coenzyme A with … Continue reading
Glutamate Synthases are key enzymes in the early stages of the assimilation of ammonia in bacteria, yeast, and plants. Azospirillum brasilense glutamate synthase (GltS) is a complex iron-sulfur flavoprotein that catalyzes the reductive transfer of L-glutamine amide group to the (C2) … Continue reading
The Cytochrome c (Cytc) is a small heme protein of ~100 amino acids. It presents in the mitochondrion of eukaryotic cells and it is loosely associated with their inner membrane. Cytc is highly water-soluble and is an essential component of … Continue reading
Experimental studies on peptides and proteins stability and folding in solution are usually made in the presence of membrane mimic nonaqueous solvents. These conditions facilitate the study of hydrophobic stabilization effects.
sMy research on peptides is focused on those that are able to form secondary structure elements in solution like -turn, -helix and -strands. The purpose of these investigations was to establish the stability of this peptide in view of its … Continue reading