Category Archives: Research

Molekulare Maschinen: Die Coronavirus SARS-CoV-2 Bedrohung, Teil I.

Was Freunde mit und für uns tun, ist auch ein Erlebtes; denn es stärkt und fördert unsere Persönlichkeit. Was Feinde gegen uns unternehmen, erleben wir nicht, wir erfahren’s nur, lehnen’s ab und schützen uns dagegen wie gegen Frost, Sturm, Regen … Continue reading

Posted in Research, Science Topics, What is new | Leave a comment

Le Macchine Molecolari: La minaccia del Coronavirus SARS-CoV-2. Parte I

Difficilmente è vinto colui che sa conoscere le forze sue e quelle del nemico. Nicollò Machiavelli in Dell’arte della guerra (1519-1520) Un virus è la vita nella forma più semplice. È la riduzione minimalista di un organismo ai suoi elementi … Continue reading

Posted in Research, Science Topics | Leave a comment

Molecular Machines: the Coronavirus SARS-CoV-2 Menace. Part I

“If you know the enemy and know yourself, you need not fear the result of a hundred battles. If you know yourself but not the enemy, for every victory gained you will also suffer a defeat. If you know neither … Continue reading

Posted in Research, Science Topics, What is new | Tagged , | Leave a comment

A personal tribute to the founder of MD simulation of biological molecules: Prof Herman J.C. Berendsen (1934-2019)

On the 7 October 2019, Prof Dr Herman Johan Christiaan Berendsen passed away just shortly after his 85 birthday. Prof Berendsen is considered the founder of the molecular dynamics simulation of biological system: the area of theoretical research that also … Continue reading

Posted in Research, What is new | 2 Comments

The Almighty​ Curcumin

Curcumin is a polyphenol derived from the root of turmeric (Curcuma longa) that it is widely used as a dietary spice and natural food colouring agent throughout the world.

Posted in Research, What is new | Tagged | Leave a comment

Modular Assembly of Proteins on Nanoparticles

I have recently contributed to a proof of concept study published in the prestigious Nature Communication (doi:10.1038/s41467-018-03931-4) [1]. The study involved collaborations with experimental groups across the University of Lincoln (UoL), University of Molise (Italy) and the Royal Holloway University … Continue reading

Posted in Research, Science Topics | Leave a comment

The Protein Engineering of a controllable Nano-Gate: the FhuA D1– 160 channel

The confinement of primeval biochemical compounds by nano compartmentalization made possible the spatial and temporal control and the development possible the most complex chemical process: the life.

Posted in Research, Science Topics | Leave a comment

Bioinformatics Tools for Protein Engineering​: The MAP server

Mutagenesis Assistant Program (MAP) is a free accessible statistical tool which can be used for the benchmarking of random mutagenesis methods on the protein level. The server is currently hosted at the RTWH Aachen but it can still be accessed … Continue reading

Posted in Databases, Programming, Research, Science Topics | Leave a comment

The Arginine Deiminase​: an Anticancer Protein

Arginine deiminase (ADI, EC 3.5.3.6) is an arginine-metabolizing hydrolase that catalyzes the hydrolysis of the amino acid L-arginine to form citrulline and ammonia.

Posted in Research, Science Topics | Leave a comment

Il calcolo delle cariche parziali atomiche

Le cariche parziali da usare nel campo di forze si ottengono generalmente da calcoli quantomeccanici. Nel caso di molecole rigide, il calcolo delle cariche è abbastanza semplice. Nel caso di molecole flessibili, occorre valutare quanto le diverse conformazioni influenzano la … Continue reading

Posted in Research, Science Topics | Leave a comment